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Apr 22, 2025

April 2025 Newsletter: Weight‑Loss Drugs, Testosterone & More

With 2025 underway, a few items to share that I hope you find of interest...

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With 2025 underway, a few items to share that I hope you find of interest.

The GLP‑1 (Glucagon Like Peptide‑1) agonists branded as Wegovy, Ozempic, Rybelsus, Mounjaro, Zepbound, Victoza, Saxenda, Trulicity, Byetta, Bydureon, Adlyxin have received much attention over the last several months for good reason.

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Testosterone Topics

Prostate Cancer

At Duke University, researchers brought to light the mechanisms by which we observe that low testosterone leads to prostate cancer and higher levels of testosterone can prevent and actually be used to successfully treat (using “bipolar therapy”) prostate cancer.

Thrombosis (blood clots) & Blood Viscosity (“thickness”)

Testosterone Replacement Therapy does NOT create blood clots, nor does increased blood “thickness” necessarily lead to blood clots.

Exercise, Vitamin D3, Omega-3 fats and Aging

Fisetin for Senescent Cells

Protein

Telmisartan

VO2 max and Healthspan

New approach to a common issue

Friends Doing Extraordinary Things

For the Bicyclists

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Best in health,

Rand McClain, D.O.

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